Operon AI Experiments

Generate grounded, lab-executable plans from scientific hypotheses.

Past Experiments

HypothesisNoveltyScoreStatusDate

Lactobacillus rhamnosus GG supplementation in C57BL/6 mice will intestinal permeability me…SIMILAR EXISTS ▲78review29 Apr continuous cathode polarization at -400mV in Sporomusa ovata in strictly anaerobic reactor…SIMILAR EXISTS ▲82review29 Apr Generatively redesigned T7-gp17 RBD distal tip loops (466-553) targeting P. aeruginosa Opr…SIMILAR EXISTS ▲82review28 Apr activating Wnt signaling with ligand in intestinal organoids will expression of Wnt target…SIMILAR EXISTS ▲85done28 Apr gene knockdown or knockout of [gene] in [cell line] will cell viability or proliferation, …SIMILAR EXISTS ▲85done28 Apr overexpressing a protein in HEK293 cells will cell proliferation, compared to untreated co…SIMILAR EXISTS ▲72done28 Apr a drug in HeLa cells will cell viability, compared to untreated cells.SIMILAR EXISTS ▲72review27 Apr mRNA in ionizable lipid nanoparticles with phospholipid:cholesterol:PEG-lipid molar ratio …SIMILAR EXISTS ▲82review26 Apr Lactobacillus rhamnosus GG supplementation in C57BL/6 mice will intestinal permeability me…SIMILAR EXISTS ▲72done26 Apr CRISPR-Cas12a lateral flow assay targeting IS6110 insertion sequence in unprocessed sputum…SIMILAR EXISTS ▲78done26 Apr Overexpression of rbcL gene from Thermosynechococcus elongatus under constitutive Ptrc pro…SIMILAR EXISTS ▲82done26 Apr security vulnerability testing in Electron application will number or severity of security…SIMILAR EXISTS ▲45critic_validation26 Apr LLMs (large language models) in AGI benchmark tasks will performance score on AGI benchmar…SIMILAR EXISTS ▲72done26 Apr small molecule compound in tumor-bearing mice will tumor volume, compared to standard of c…SIMILAR EXISTS ▲82done26 Apr drug or compound in cancer cell line will cell proliferation, compared to vehicle control.SIMILAR EXISTS ▲82done26 Apr mRNA formulated in ionizable lipid nanoparticles with phospholipid:cholesterol:PEG-lipid m…SIMILAR EXISTS ▲82done26 Apr CRISPR-Cas12a lateral flow assay targeting IS6110 insertion sequence in unprocessed sputum…SIMILAR EXISTS ▲78done26 Apr Overexpression of rbcL gene from Thermosynechococcus elongatus under constitutive Ptrc pro…SIMILAR EXISTS ▲72review26 Apr Overexpression of Thermosynechococcus elongatus rbcL (large subunit of rubisco) under cons…—82done26 Apr CRISPR-Cas12a lateral flow assay targeting IS6110 insertion sequence of Mycobacterium tube…—72done26 Apr Introducing Sporomusa ovata into a bioelectrochemical system at a cathode potential of −40…—78done26 Apr Supplementing C57BL/6 mice with Lactobacillus rhamnosus GG for 4 weeks will reduce intesti…—78done26 Apr Replacing sucrose with trehalose as a cryoprotectant in the freezing medium will increase …—78failed25 Apr How can we test whether a lipid nanoparticle formulation improves delivery efficiency for …——done25 Apr

Operon AI Guide

How To Use Operon AI

Use the dashboard to monitor novelty, critic score, and lifecycle status across saved Operon AI experiments.

1.Use the conversational intake chat to describe the intervention, model system, endpoint, and comparator in natural language.

2.Let Operon AI keep asking follow-ups until the planning brief is sufficient for a real protocol, budget, and validation design.

3.Review the synthesized hypothesis preview before starting analysis.

4.Read Literature QC before the plan appears, then inspect the final protocol, materials, timeline, and validation sections.

5.Treat the final draft as a quality-checked starting point for scientist review, not as unreviewed raw model output.

Status Glossary

pending

A record exists, but analysis has not produced a review-ready draft yet.

running

The pipeline is actively moving through intake confirmation, QC, planning, or internal QA.

completed

The pipeline finished and produced a review-ready draft after internal quality checks.

failed

A pipeline stage stopped with a persisted error. Review the failure reason before retrying.

ready

The latest draft passed internal QA and can be reviewed as a candidate plan.

legacy preview

This is a pre-pipeline record rendered for compatibility, not a full Operon AI run artifact.

Quality Score

90-100: unusually strong operational draft after internal QA.

70-89: usable draft with normal scientist review still recommended.

50-69: low-confidence draft that likely needs another repair pass or manual review.

0-49: high-risk draft that should be treated as a generation failure.

Novelty States

not found

Operon AI found no close prior protocol or paper match in the queried sources.

similar exists

Related work exists, but the hypothesis still appears meaningfully distinct in intervention, endpoint, or setup.

exact match

A close match already exists in the literature or protocol ecosystem. Treat the hypothesis as needing differentiation.